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Salinomycin

SKU: orb1224788

Description

Salinomycin is an inhibitor of Wnt/β-catenin signaling, which acts on the Wnt/Fzd/LRP complex. Salinomycin strongly suppresses Wnt1-stimulated reporter activity with an IC50 of 163 nM, and reduces β-catenin levels.

Images & Validation

Key Properties

CAS Number53003-10-4
MW751
Purity>98% (HPLC)
FormulaC??H??O??
SMILESCC[C@@H](C(O)=O)[C@H]1CC[C@@H]([C@H]([C@H]([C@@H]([C@@H](C([C@@H]([C@H]2O[C@]3([C@@H](C[C@@H]2C)C)O[C@]4([C@@H](C=C3)O)CC[C@](O4)([C@H]5CC[C@](CC)([C@@H](O5)C)O)C)CC)=O)C)O)C)O1)C
TargetWnt/beta/catenin
SolubilityDMSO:≥ 36.7mg/mL In vivo: Add solvents to the product individually and in order: 10% DMSO+40% PEG300+5% Tween-80+45% saline (clear) ≥2mg/mL ;10% DMSO+90% corn oil (clear) ≥2mg/mL

Storage & Handling

StorageStorage temperature: -20°C. Stability: ≥ 2 years
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

AHR 3096 | AHR3096 | AHR-3096 | K 364 | Salinomycin | BioCox | Sacox | Salocin | Coxistac

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Protocol Information

Available Sizes

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200 mg
500 mg
2 mg
$ 90.00
5 mg
$ 130.00
10 mg
$ 200.00
25 mg
$ 360.00
50 mg
$ 610.00
100 mg
$ 870.00