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Sal003

SKU: orb1305512

Description

Sal003

Research Area

Cell Biology, Metabolism Research

Images & Validation

Key Properties

CAS Number1164470-53-4
MW463.21
Purity98.58% (May vary between batches)
FormulaC18H15Cl4N3OS
SMILESClc1ccc(NC(=S)NC(NC(=O)\C=C\c2ccccc2)C(Cl)(Cl)Cl)cc1
TargetApoptosis,PERK,Phosphatase
Solubility10% DMSO+90% Corn Oil:2 mg/mL (4.32 mM);DMSO:46.3 mg/mL (99.95 mM)

Bioactivity

In Vivo
In mouse embryonic fibroblasts, Sal003 induced depolymerization of polysaccharides by increasing the phosphorylation of eIF2a. Sal003 increased eIF2a phosphorylation by blocking eIF2a phosphodiesterase activity, and Sal003 enhanced the apoptotic signaling pathway induced by cytotoxicity by induced phosphorylation of eIF2α.
In Vitro
In mouse embryonic fibroblasts, Sal003 induced depolymerization of polysaccharides by increasing the phosphorylation of eIF2a. Sal003 increased eIF2a phosphorylation by blocking eIF2a phosphodiesterase activity, and Sal003 enhanced the apoptotic signaling pathway induced by cytotoxicity by induced phosphorylation of eIF2α.

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

Apoptosis, Inhibitor, eIF-2α phosphatase, inhibit, Sal 003, Sal003, Sal-003, Phosphatase

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Quality Guarantee

Quality Guarantee

Explore bioreagents carefree to elevate your research. All our products are rigorously tested for performance. If a product does not perform as described on its datasheet, our scientific support team will provide expert troubleshooting, a prompt replacement, or a refund. For full details, please see our Terms & Conditions and Buying Guide. Contact us at [email protected].

Key Properties

No computed properties available.

Protocol Information

Available Sizes

Select a size below

1 mg
$ 80.00
2 mg
$ 90.00
1 ml x 10 mM (in DMSO)
$ 110.00
5 mg
$ 110.00
10 mg
$ 150.00
25 mg
$ 240.00
50 mg
$ 330.00
100 mg
$ 470.00
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