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| Catalog Number | orb1824399 |
|---|---|
| Category | Antibodies |
| Description | S100A12 (CGRP) is a calcium-, zinc- and copper-binding protein which plays a prominent role in the regulation of inflammatory processes and immune response. Its pro-inflammatory activity involves recruitment of leukocytes, promotion of cytokine and chemokine production, and regulation of leukocyte adhesion and migration. |
| Clonality | Monoclonal |
| Species/Host | Mouse |
| Isotype | Mouse IgG1, kappa |
| Conjugation | Unconjugated |
| Reactivity | Human |
| Immunogen | A recombinant partial protein sequence (within amino acids 1-95) from the human protein was used as the immunogen for the S100A12 antibody. |
| UniProt ID | P80511 |
| Tested applications | IHC-P |
| Dilution range | Immunohistochemistry (FFPE): 1-2ug/ml for 30 min at RT |
| Antibody Type | Primary Antibody |
| Clone Number | S100A12/4514 |
| Formula | 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Note | For research use only |
| Expiration Date | 12 months from date of receipt. |

IHC staining of FFPE human placental tissue with S100A12 antibody (clone S100A12/4514). Inset: PBS used in place of primary Ab (secondary Ab negative control). HIER: boil tissue sections in pH9 10 mM Tris with 1 mM EDTA for 20 min and allow to cool before testing.

SDS-PAGE analysis of purified, BSA-free S100A12 antibody (clone S100A12/4514) as confirmation of integrity and purity.
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