S0859

SKU: orb1306753

Description

S0859 is a small molecule N-cyanosulphonamide that acts as a potent and selective inhibitor of the sodium/bicarbonate cotransporter NBC (SLC4A7). This inhibitor is a valuable research tool for studying intracellular pH regulation in both cellular and animal models of diseases such as cancer and ischemia.

Research Area

Pharmacology & Drug Discovery

Key Properties

• CAS Number: 1019331-10-2
• MW: 530.04
• Purity: 98.95%
• Formula: C₂₉H₂₄ClN₃O₃S
• SMILES: Cc1ccc(CN(Cc2ccc(cc2)-c2ccccc2S(=O)(=O)NC#N)C(=O)c2ccccc2Cl)cc1
• Target: Sodium Channel,Others
• Solubility: DMSO:<5.3 mg/mL (10 mM)

Storage & Handling

• Storage: Pure form: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

inhibit, NBC, Na+/HCO3- Cotransporter, Na/HCO3 cotransporter, Inhibitor, S 0859, S0859, S-0859

Compound Identifiers

PubChem CID

70675849