(S)-(+)-Ketoprofen

SKU: orb1225632

Description

Ketoprofen, a propionic acid derivative, is a nonsteroidal anti-inflammatory agent (NSAIA) with analgesic and antipyretic properties.(In Vitro):S-(+)-Ketoprofen (Compound 1) is a potent inhibitor of both COX-1 and COX-2 with IC50s of 1.9 and 27 nM, respectively.

Research Area

Pharmacology & Drug Discovery

Key Properties

• CAS Number: 22161-81-5
• MW: 254.3
• Purity: >98% (HPLC)
• Formula: C₁₆H₁₄O₃
• SMILES: C[C@@H](C1=CC=CC(=C1)C(=O)C2=CC=CC=C2)C(=O)O
• Target: COX
• Solubility: Water: 51 mg/L (at 22 °C)

Bioactivity

• In Vitro:
  S-(+)-Ketoprofen (Compound 1) is a potent inhibitor of both COX-1 and COX-2 with IC50s of 1.9 and 27 nM, respectively.

Storage & Handling

• Storage: Storage temperature: -20°C. Stability: ≥ 2 years
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

(S)-2-(3-benzoylphenyl)Propionic Acid | Dexketoprofen

Quick Database Links

Gene Symbol

COX