(S)-GSK-3685032

SKU: orb3145373

Description

(S)-GSK-3685032 is an isomer of GSK-3685032 and serves as a control compound in experiments. GSK-3685032 is a selective inhibitor of DNMT1, characterized by its non-time-dependent, non-covalent, and reversible nature, with an IC50 of 0.036 μM. It induces loss of DNA methylation, transcription activation, and inhibition of cancer cell growth.

Research Area

Epigenetics & Chromatin

Key Properties

• CAS Number: 2170142-58-0
• MW: 420.53
• Formula: C₂₂H₂₄N₆OS
• SMILES: C(#N)C1=C(N=C(S[C@H](C(N)=O)C2=CC=CC=C2)C(C#N)=C1CC)N3CCC(N)CC3
• Target: DNA Methyltransferase

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

DNA Methyltransferase