(S)-GSK-3685032

SKU: orb2703154

Description

(S)-GSK-3685032 is the isomer of GSK-3685032 (HY-139664), and can be used as an experimental control. GSK-3685032 is a non-time-dependent, noncovalently, first-in-class reversible DNMT1-selective inhibitor, with an IC50 of 0.036 μM. GSK-3685032 induces robust loss of DNA methylation, transcriptional activation, and cancer cell growth inhibition.

Key Properties

• CAS Number: 2170142-58-0
• MW: 420.530562400818
• Purity: >98%
• Formula: C₂₂H₂₄N₆OS
• SMILES: C(C1C(=C(C#N)C(S[C@@H](C2C=CC=CC=2)C(=O)N)=NC=1N1CCC(N)CC1)CC)#N

Storage & Handling

• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

132233898