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(S)-GSK-3685032

SKU: orb2703154

Description

(S)-GSK-3685032 is the isomer of GSK-3685032 (HY-139664), and can be used as an experimental control. GSK-3685032 is a non-time-dependent, noncovalently, first-in-class reversible DNMT1-selective inhibitor, with an IC50 of 0.036 μM. GSK-3685032 induces robust loss of DNA methylation, transcriptional activation, and cancer cell growth inhibition.

Images & Validation

Key Properties

CAS Number2170142-58-0
MW420.530562400818
Purity>98%
FormulaC22H24N6OS
SMILESC(C1C(=C(C#N)C(S[C@@H](C2C=CC=CC=2)C(=O)N)=NC=1N1CCC(N)CC1)CC)#N

Storage & Handling

Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Key Properties

No computed properties available.

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Protocol Information

(S)-GSK-3685032 (orb2703154)

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100 mg
$ 1,140.00
250 mg
$ 2,000.00
1 g
$ 4,350.00
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