RUNX1/RUNX2/RUNX3 Rabbit mAb [KD Validated] Antibody

SKU: orb1727594

Description

RUNX2 regulates the transcription of various genes including osteopontin, bone sialoprotein, and osteocalcin via binding to the core site of the enhancers or promoters.RUNX3/AML2 is a member of the Runt family of transcription factors. RUNX3 is important for the suppression of cell proliferation in the gastric epithelium, neurogenesis of the dorsal root ganglia, and T cell differentiation.

Images & Validation

• Tested Applications: FC, ICC, IHC, IP, WB
• Dilution range: WB:1:500~1:2000IHC:1:50~1:200ICC/IF:1:50~1:200IP:1:50
• Reactivity: Human, Mouse, Rat

Key Properties

• Antibody Type: Recombinant Antibody
• Host: Rabbit
• Clonality: Monoclonal
• Isotype: Rabbit IgG
• Immunogen: A synthesized peptide derived from human RUNX1/RUNX2/RUNX3
• Molecular Weight: 51kDa
• Purification: Affinity-chromatography
• Conjugation: Unconjugated

Storage & Handling

• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Form/Appearance: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Disclaimer: For research use only

Alternative Names

RUNX1; AML1; RUNX2; OSF2; RUNX3; CBFA3;

All lanes use the Antibody at 1:1K dilution for 1 hour at room temperature.

Immunohistochemical analysis of paraffin-embedded mouse lung, using RUNX1/RUNX2/RUNX3 Antibody.

Western blot analysis of RUNX1/RUNX2/RUNX3 expression in MOLT4 cell lysate.

Quick Database Links

UniProt

Q13950, Q13761, Q01196