RU-301

SKU: orb1299830

Description

RU-301 is a small molecule pan-TAM receptor tyrosine kinase inhibitor used in research. It is applied in oncology and immunology studies to investigate tumor microenvironment modulation and macrophage polarization in both in vitro cellular assays and in vivo animal models.

Research Area

Signal Transduction

Key Properties

• CAS Number: 1110873-99-8
• MW: 480.46
• Purity: 98.87%
• Formula: C₂₁H₁₉F₃N₄O₄S
• SMILES: Cc1cc(CSc2ccccc2C(=O)NCCNc2ccc(cc2[N+]([O-])=O)C(F)(F)F)on1
• Target: TAM Receptor
• Solubility: 10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.16 mM);DMSO:30 mg/mL (62.44 mM)

Bioactivity

• Target IC50:
  TAM:10 μM (IC50)

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Tyro3, TGFβ1, TAM, TAM Receptor, TAMReceptor, RU 301, RU301, RU-301, Axl, cancer, H1299, ERK, Gas6, Inhibitor, NASH, pan-TAM receptor, inhibit, Mer

Compound Identifiers

PubChem CID

40135492