RSK1(Phospho-Ser380) Rabbit mAb [KD Validated]

• Catalog Number: orb1727780
• Category: Antibodies
• Description: Rsk1 is a member of a family of 90kDa ribosomal protein S6 kinases, which includes Rsk1, Rsk2 and Rsk3. These are broadly expressed serine / threonine protein kinases activated in response to mitogenic stimuli, including extracellular signal regulated protein kinases Erk1 and Erk2. Rsk1 is activated by MAPK in vitro and in vivo via phosphorylation. Active Rsks appear to play a major role in transcriptional regulation by translocating to the nucleus and phosphorylating c-Fos and CREB.
• Species/Host: Rabbit
• Clonality: Recombinant
• Tested applications: ICC, IP, WB
• Reactivity: Human, Mouse, Rat
• Isotype: Rabbit IgG
• Immunogen: A synthesized peptide derived from human Phospho-RSK1(S380)
• Antibody Type: Recombinant Antibody
• Dilution range: WB:1:500~1:2000ICC/IF:1:50~1:200IP:1:50
• Form/Appearance: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Conjugation: Unconjugated
• MW: 90kDa
• UniProt ID: Q15418
• Source: Recombinant Rabbit
• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Alternative names: RSK; HU-1; RSK1; MAPKAPK1A; RPS6KA1;
• Note: For research use only
• Expiration Date: 12 months from date of receipt.

All lanes use the Antibody at 1:1K dilution for 1 hour at room temperature.

Western blot analysis of Phospho-RSK1(S380) expression in A431 cell lysate treated with EGF.