RO7185876

SKU: orb1691119

Description

RO7185876 is a selective gamma secretase modulator investigated for Alzheimer's disease research. It is utilized in both in vitro and in vivo studies to explore its effects on amyloid-beta peptide production and disease pathology.

Research Area

Neuroscience, Protein Biochemistry, Stem Cell & Developmental Biology

Key Properties

• CAS Number: 2226038-71-5
• MW: 483.532
• Purity: 99.50% (May vary between batches)
• Formula: C₂₅H₂₈F₃N₇
• SMILES: N(C=1N=C2[C@@H](CCCCN2N1)C3=C(F)C(F)=C(F)C=C3)[C@H]4[C@@]5(CN(C[C@]4(CC5)[H])C=6C=C(C)N=CN6)[H]
• Target: Gamma-secretase
• Solubility: DMSO:25 mg/mL (51.7 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.14 mM)

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Gammasecretase, RO 7185876, RO7185876, RO-7185876, γ secretase

Compound Identifiers

PubChem CID

139488755