(9R)-RO7185876

SKU: orb2945730

Description

(9R)-RO7185876 is a potent and selective γ-secretase inhibitor that effectively reduces Aβ42 peptide production. This small molecule is a valuable research tool for investigating the pathogenesis of and potential treatments for Alzheimer's disease, cerebral amyloid angiopathy, and related neurodegenerative disorders in both cellular and animal models.

Research Area

Neuroscience, Protein Biochemistry, Stem Cell & Developmental Biology

Key Properties

• CAS Number: 2226077-86-5
• MW: 483.532
• Formula: C₂₅H₂₈F₃N₇
• SMILES: N(C=1N=C2[C@H](CCCCN2N1)C3=C(F)C(F)=C(F)C=C3)[C@H]4[C@@]5(CN(C[C@]4(CC5)[H])C=6C=C(C)N=CN6)[H]
• Target: Gamma-secretase,Beta Amyloid

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

139488618