RNF5 agonist 1

SKU: orb2814211

Description

RNF5 agonist 1 (analog-1) is a potent small molecule agonist derived from the RNF5 inhibitor inh-02. In CFBE41o- cells expressing F508del-CFTR, it promotes the ubiquitination of ATG4B. This activity makes it a valuable research tool for studying RNF5-mediated pathways in autophagy and cystic fibrosis-related cellular models.

Research Area

Pharmacology & Drug Discovery; Cell Biology, Protein Biochemistry

Key Properties

• CAS Number: 69909-92-8
• MW: 370.47
• Formula: C₂₂H₁₈N₄S
• SMILES: N=1SC(=NC(=NC=2C=CC=CC2)C=3C=CC=CC3)N(C=4C=CC=CC4)C1C
• Target: E1/E2/E3 Enzyme

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

4253703