(E),(Z)-RNF5 agonist 1

SKU: orb3174992

Description

(E),(Z)-RNF5 agonist 1 (Compound Analog-1) is an RNF5 agonist that enhances the ubiquitin-mediated degradation of the SARS-CoV-2 E protein. It effectively inhibits SARS-CoV-2 replication and significantly reduces lung pathology and systemic inflammation in mouse infection models. Additionally, (E),(Z)-RNF5 agonist 1 exhibits potent cytotoxicity against neuroblastoma and melanoma cells. This compound is relevant for cancer and antiviral research.

Key Properties

• CAS Number: 2231731-82-9
• MW: 370.47
• Formula: C₂₂H₁₈N₄S
• SMILES: N(\C(=N\C1=CC=CC=C1)\C2=CC=CC=C2)=C\3/N(C(C)=NS3)C4=CC=CC=C4
• Target: E1/E2/E3 Enzyme,SARS-CoV

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

E1/E2/E3 Enzyme,SARS-CoV