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RIP1 kinase inhibitor 1

SKU: orb1708675

Description

This small molecule is a potent, orally bioavailable, and brain-penetrant RIP1 kinase inhibitor (pKi = 9.04). It is a valuable research tool for investigating necroptosis and inflammation in both cellular assays and animal models of neurological and systemic diseases.

Research Area

Cell Biology, Pharmacology & Drug Discovery, Signal Transduction

Images & Validation

Key Properties

CAS Number2095515-38-9
MW461.9
FormulaC24H20ClN5O3
SMILESCN1c2ccc(cc2OC[C@H](N2CCc3c(Cl)n(Cc4ccccc4)nc3C2=O)C1=O)C#N
TargetOthers,RIP kinase

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Quality Guarantee

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Key Properties

No computed properties available.

Protocol Information