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Catalog Number | orb1308130 |
---|---|
Category | Small Molecules |
Description | Ribociclib succinate |
CAS Number | 1374639-75-4 |
Purity | 99.57% |
MW | 552.63 |
SMILES | OC(=O)CCC(O)=O.CN(C)C(=O)c1cc2cnc(Nc3ccc(cn3)N3CCNCC3)nc2n1C1CCCC1 |
Formula | C27H36N8O5 |
Biological Activity | Ribociclib succinate (LEE011 succinate) is a highly specific CDK4/6 inhibitor (IC50: 10 nM and 39 nM, respectively). It also is over 1,000-fold less potent against the cyclin B/CDK1 complex. |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
> 98% (HPLC) | |
1374639-75-4 |
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