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Catalog Number | orb1707086 |
---|---|
Category | Small Molecules |
Description | Ribociclib succinate hydrate |
CAS Number | 1374639-79-8 |
Purity | 98% |
MW | 570.64 |
SMILES | O=C(N(C)C)C(N1C2CCCC2)=CC(C1=N3)=CN=C3NC(N=C4)=CC=C4N5CCNCC5.OC(CCC(O)=O)=O.[F,Cl,Br,I].O |
Formula | C27H38N8O6 |
Biological Activity | Ribociclib succinate hydrate is a highly specific CDK4/6 inhibitor (IC50s: 10 nM and 39 nM, respectively). It also is over 1,000-fold less potent against the cyclin B/CDK1 complex. |
Storage | -20°C |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |