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RI-2

SKU: orb1305247

Description

RI-2 is a potent and selective RAD51 inhibitor that disrupts homologous recombination (HR) DNA repair in human cells, exhibiting an IC50 of 44.17 μM. It is a valuable research tool for studying DNA repair mechanisms and for sensitizing cancer cells to radiation and genotoxic agents in vitro.

Research Area

Cell Biology, Molecular Biology

Images & Validation

Key Properties

CAS Number1417162-36-7
MW433.28
Purity98.85%
FormulaC21H18Cl2N2O4
SMILESCOc1ccc(cc1)C1=C(N2CCOCC2)C(=O)N(C1=O)c1ccc(Cl)c(Cl)c1
TargetDNA/RNA Synthesis
SolubilityDMSO:50 mg/mL (115.4 mM)

Bioactivity

Target IC50
RAD51:44.17 μM

Storage & Handling

StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

RAD51, RI 2, RI2, RI-2, RNA Synthesis, RNASynthesis, DNASynthesis, DNA Synthesis, inhibit, Inhibitor

Similar Products

  • RI-2 [orb1223316]

    >98% (HPLC)

    1417162-36-7

    433.28

    C21H18Cl2N2O4

    1 g, 500 mg, 200 mg, 2 mg, 5 mg, 10 mg, 25 mg, 50 mg, 100 mg
Quality Guarantee

Quality Guarantee

Explore bioreagents carefree to elevate your research. All our products are rigorously tested for performance. If a product does not perform as described on its datasheet, our scientific support team will provide expert troubleshooting, a prompt replacement, or a refund. For full details, please see our Terms & Conditions and Buying Guide. Contact us at [email protected].

Key Properties

No computed properties available.

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RI-2 (orb1305247)

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% DMSO +
%+
% Tween 80 +
%

Available Sizes

Select a size below

1 mg
$ 110.00
2 mg
$ 140.00
5 mg
$ 210.00
1 ml x 10 mM (in DMSO)
$ 220.00
10 mg
$ 340.00
25 mg
$ 500.00
50 mg
$ 720.00
100 mg
$ 1,000.00
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