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Rhosin

SKU: orb1706719

Description

Rhosin is a potent and selective small molecule inhibitor of RhoA subfamily GTPases, binding specifically to RhoA (Kd ~0.4 µM) to disrupt RhoA-GEF interactions. It has been utilized in vitro to study RhoA-mediated cytoskeletal dynamics and cell adhesion, and has shown efficacy in inducing apoptosis in various cancer cell lines.

Research Area

Cell Biology, Pharmacology & Drug Discovery, Signal Transduction

Images & Validation

Key Properties

CAS Number1173671-63-0
MW358.4
FormulaC20H18N6O
SMILESC([C@H](C(N/N=C/C1=CC2=C(C=C1)N=CC=N2)=O)N)C=3C=4C(NC3)=CC=CC4
TargetRho,Ras,Apoptosis

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Quality Guarantee

Quality Guarantee

Explore bioreagents carefree to elevate your research. All our products are rigorously tested for performance. If a product does not perform as described on its datasheet, our scientific support team will provide expert troubleshooting, a prompt replacement, or a refund. For full details, please see our Terms & Conditions and Buying Guide. Contact us at [email protected].

Key Properties

No computed properties available.

Protocol Information

Available Sizes

Select a size below

5 mg
$ 660.00
10 mg
$ 1,060.00
50 mg
$ 2,920.00
100 mg
$ 5,730.00
DispatchUsually dispatched within 6-8 weeks
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