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RGB-286638

SKU: orb1744363

Description

RGB-286638 is a potent multi-target CDK inhibitor with low nanomolar IC50 values against key cyclin-CDK complexes (CDK9, CDK1, CDK2, CDK4, CDK3, CDK5) and kinases like GSK-3β and TAK1. Its broad profile supports research into cell cycle regulation, transcription, and signaling pathways in both in vitro and in vivo models of cancer and neurodegenerative diseases.

Research Area

Cardiovascular Research, Cell Biology, Epigenetics & Chromatin, Signal Transduction, Stem Cell & Developmental Biology

Images & Validation

Key Properties

CAS Number784210-87-3
MW618.55
FormulaC29H37Cl2N7O4
SMILESCl.Cl.O=C(NC1=CC=CC=2C=3NN=C(C=4C=CC(=CC4)CN5CCN(CCOC)CC5)C3C(=O)C12)NN6CCOCC6
TargetOthers,GSK-3,JAK,MEK,CDK

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Quality Guarantee

Quality Guarantee

Explore bioreagents carefree to elevate your research. All our products are rigorously tested for performance. If a product does not perform as described on its datasheet, our scientific support team will provide expert troubleshooting, a prompt replacement, or a refund. For full details, please see our Terms & Conditions and Buying Guide. Contact us at [email protected].

Key Properties

No computed properties available.

Protocol Information

Available Sizes

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5 mg
$ 330.00
10 mg
$ 480.00
25 mg
$ 960.00
DispatchUsually dispatched within 10-14 weeks
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