Recombinant Ornithine Decarboxylase Antibody / ODC1

SKU: orb2634952

Description

Recognizes a 51-53kDa protein, identified as the Ornithine Decarboxylase (ODC-1). ODC is the initial and rate-limiting enzyme in the biosynthetic pathway of polyamines and is involved in the conversion of ornithine to putrescine. The biological activity of ODC-1 is rapidly induced in response to virtually all agents known to promote cell proliferation including hormones, drugs, growth factors, mitogens, and tumor promoters. Reportedly, ODC mRNA levels are elevated in lung carcinomas as well as in colon adenomas and carcinomas. ODC activity in colorectal carcinomas is greater than those in adenomas and normal mucosa.

Images & Validation

• Tested Applications: ELISA, WB
• Dilution Range: ELISA (order BSA-free format for coating),Western blot: 1-2ug/ml
• Reactivity: Human
• Application Notes:
  Optimal dilution of the recombinant Ornithine Decarboxylase antibody should be determined by the researcher.

Key Properties

• Antibody Type: Primary Antibody
• Host: Mouse
• Clonality: Recombinant
• Isotype: Mouse IgG1, kappa
• Clone No.: rODC1/487
• Immunogen: Recombinant full-length human protein was used as the immunogen for the recombinant Ornithine Decarboxylase antibody.
• Purification: Protein A/G affinity
• Conjugation: Unconjugated

Storage & Handling

• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Buffer/Preservatives: 1 mg/ml in 1X PBS; rAlbumin free, sodium azide free
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Western blot analysis of human PC3 cell lysate using recombinant Ornithine Decarboxylase antibody (clone rODC1/487). Predicted molecular weight ~51 kDa.

SDS-PAGE analysis of purified, BSA-free recombinant Ornithine Decarboxylase antibody (clone rODC1/487) as confirmation of integrity and purity.

Quick Database Links

UniProt

P11926