Rasagiline

SKU: orb1309706

Description

Rasagiline (AGN1135) is a selective, irreversible monoamine oxidase B inhibitor used in Parkinson's disease research. It is studied as an adjunct to levodopa/carbidopa therapy and is applied in both in vitro enzymatic assays and in vivo models of neurodegeneration to investigate neuroprotective mechanisms.

Research Area

Cell Biology, Metabolism Research, Neuroscience

Key Properties

• CAS Number: 136236-51-6
• MW: 171.24
• Purity: 99.87% (May vary between batches)
• Formula: C₁₂H₁₃N
• SMILES: C#CCN[C@@H]1CCC2=C1C=CC=C2
• Target: Bcl-2 Family,MAO,Monoamine Oxidase
• Solubility: H2O:23.4 mM;DMSO:50 mg/mL (291.99 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (11.68 mM)

Bioactivity

• Target IC50:
  MAO-A:412 nM|MAO-B:4.43 nM

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Rasagiline, TVP 1012, TVP1012, TVP-1012, AGN1135, AGN-1135, AGN 1135, (R)-AGN1135, Bcl-2, MonoamineOxidase, Monoamine Oxidase, inhibit, Inhibitor, MAO, MAO-B, MAO-A

Compound Identifiers

PubChem CID

3052776