Ras Inhibitory Peptide

SKU: orb1692898

Description

This synthetic peptide, containing the PVPPR sequence, acts as a specific inhibitor of the Sos1-Grb2 interaction, thereby blocking Ras activation downstream of receptor tyrosine kinases like EGFR. It is a valuable tool for investigating Ras/ERK signaling pathways in both cellular and animal models of cancer and proliferation.

Research Area

Pharmacology & Drug Discovery, Signal Transduction

Key Properties

• Target: Ras,Others
• CAS Number: 159088-48-9
• MW: 1170.433
• Formula: C₅₃H₉₁N₁₉O₁₁
• SMILES: CC(C)[C@H](N)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N[C@@H](C(C)C)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(O)=O |@@:30|

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

444408