KS-58

SKU: orb2813708

Description

KS-58 is a cell-permeable, inhibitory peptide derived from KRpep-2d that selectively targets K-Ras(G12D). It disrupts Ras-effector protein interactions, inhibiting tumor cell proliferation and demonstrating antitumor activity in research models for studying oncogenic signaling pathways.

Research Area

Pharmacology & Drug Discovery, Signal Transduction

Key Properties

• Target: Ras
• CAS Number: 2549046-46-8
• MW: 1333.59
• Formula: C₆₄H₈₉FN₁₂O₁₄S₂
• SMILES: C(C=1C=2C(NC1)=CC=CC2)[C@@H]3NC(=O)[C@]4(N(C(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC5=CC=C(F)C=C5)NC(=O)[C@H](CO)NC(=O)[C@H](CCCCCCC)NC(=O)[C@@]6(CSCCCSC[C@@](NC3=O)(C(=O)NCCC(=O)N7[C@](C(=O)N[C@@H](CCCC)C(=O)N6)(CCC7)[H])[H])[H])CCC4)[H]

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

172677521