Rabbit polyclonal antibodies to Morphine

SKU: orb2284546

Description

Morphine, the most powerful opiate analgesic drug in opium, acts directly on synapses of the arcuate nuclei within the central nervous system to relieve pain. It is a highly addictive drug, to which tolerance as well as physical and psychological dependences quickly develop. Administered as intravenous, subcutaneous or epidural injections, Morphine creates a profound contraction sensation in the muscles due to histamine release and also produces a "rush" mediated by different receptors in the central nervous system. Morphine is a phenanthrene opioid receptor agonist. By binding to µ opioid receptors within the central nervous system associated with analgesia, sedation, physical dependence and respiratory depression, the euphoric effects of Morphine are quickly followed by withdrawal symptoms.

Research Area

Pharmacology & Drug Discovery

Images & Validation

• Tested Applications: ELISA, WB
• Dilution Range: Western blot: 0.1-1.0 µg/ml

Key Properties

• Antibody Type: Primary Antibody
• Host: Rabbit
• Clonality: Polyclonal
• Isotype: IgG/IgM
• Immunogen: Morphine-6-Hemisuccinate conjugated to Ovalbumin
• Target: Morphine
• Molecular Weight: 285 Da
• Purification: Protein A then Immunogen affinity column
• Conjugation: Unconjugated

Storage & Handling

• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Form/Appearance: Liquid
• Buffer/Preservatives: Glycine pH 7.2
• Concentration: Batch dependent within range 2.0-2.5 mg/mL
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

Morphine