R 715 TFA

SKU: orb1980113

Description

R 715 is a potent bradykinin B1 receptor antagonist (pA2 = 8.49) with demonstrated efficacy in vitro on human umbilical cord contractions and in vivo for analgesia in diabetic neuropathy and symptom mitigation in an EAE mouse model, indicating research applications in pain and neuroinflammation.

Research Area

Immunology & Inflammation

Key Properties

• MW: 1140.33
• Formula: C₅₇H₈₁N₁₃O₁₂.XCF₃COOH
• SMILES: O=C(N1[C@@H](CCC1)C(NCC(N[C@H](C(N[C@@H](CO)C(N[C@@H](C(N[C@H](C(O)=O)[C@@H](C)CC)=O)CC2=CC3=C(C=CC=C3)C=C2)=O)=O)CC4=CC=CC=C4)=O)=O)[C@H]5N(CCC5)C([C@H](CCCNC(N)=N)NC([C@@H](NC(C)=O)CCCCN)=O)=O.OC(C(F)(F)F)=O

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

71311917