R715 TFA(185052-09-9 free base)

SKU: orb1296425

Description

R715 TFA (185052-09-9 free base) is a potent, selective, and metabolically stable bradykinin B1 receptor antagonist (pA2 = 8.49) with no activity at B2 receptors. It is used in research on neuropathic pain, demonstrated by its ability to reduce mechanical hypernociception in murine models.

Research Area

Pharmacology & Drug Discovery

Key Properties

• Target: Bradykinin Receptor
• Molecular Weight: 1254.36
• Purity: 100.00%
• Formula: C₅₉H₈₂F₃N₁₃O₁₄
• SMILES: CC[C@H](C)[C@@H](C(=O)O)NC(=O)[C@@H](CC1=CC2=CC=CC=C2C=C1)NC(=O)[C@H](CO)NC(=O)[C@H](CC3=CC=CC=C3)NC(=O)CNC(=O)[C@@H]4CCCN4C(=O)[C@@H]5CCCN5C(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CCCCN)NC(=O)C.OC(C(F)(F)F)=O

Storage & Handling

• Storage: keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Disclaimer: For research use only

Alternative Names

BradykininReceptor, bradykinin B1, Bradykinin Receptor, R 715, R715, R-715, R715 TFA(185052 09 9 free base), R715 TFA(185052099 free base), R-715 TFA(185052-09-9 free base), R715 TFA(185052-09-9 free base)

Compound Identifiers

PubChem CID

71311917