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Pyridostatin hydrochloride

SKU: orb1745066

Description

Pyridostatin (RR82) hydrochloride, a G-quadruplex DNA stabilizing agent (Kd = 490 nM), induces replication- and transcription-dependent DNA damage, promoting growth arrest in human cancer cells. It specifically targets the proto-oncogene Src, leading to reduced SRC protein levels and decreased SRC-dependent cellular motility in human breast cancer cells.

Research Area

Cell Biology, Molecular Biology

Images & Validation

Key Properties

CAS Number1781882-65-2
MW778.94
FormulaC31H37Cl5N8O5
SMILESCl.Cl.Cl.Cl.Cl.NCCOc1cc(nc(c1)C(=O)Nc1cc(OCCN)c2ccccc2n1)C(=O)Nc1cc(OCCN)c2ccccc2n1
TargetDNA/RNA Synthesis,Others

Storage & Handling

Storage-20°C
DisclaimerFor research use only

Similar Products

  • Pyridostatin (RR82) [orb1220174]

    >98% (HPLC)

    1781882-65-2

    778.9

    C₃₁H₃₇Cl₅N₈O₅

    5 mg, 10 mg, 1 g, 500 mg, 200 mg, 100 mg
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Pyridostatin hydrochloride (orb1745066)

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