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Pyr6

SKU: orb1219366

Description

Pyr6 is a selective TRPC3 inhibitor with IC50 of 0.49 uM(Ca2+ influx inhibition in thapsigargin depleted native RBL-2H3 cells).Pyr6 is an inhibitor of Ca2+ entry, which displays higher potency to inhibit Ca2+ entry mediated by CRAC channel than by TRPC3.Pyr3 is selective inhibitor of TRPC3, inhibited Orai1- and TRPC3-mediated Ca(2+) entry and currents as well as mast cell activation with similar potency.

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Key Properties

CAS Number245747-08-4
MW418.3
Purity>98% (HPLC)
FormulaC17H9F7N4O
TargetTRPC3

Storage & Handling

StorageStorage temperature: -20°C. Stability: ≥ 2 years
DisclaimerFor research use only

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Pyr6 (orb1219366)

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200 mg
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2 mg
$ 70.00
5 mg
$ 110.00
10 mg
$ 140.00
25 mg
$ 230.00
50 mg
$ 310.00
100 mg
$ 450.00