Purpurin

SKU: orb1301621

Description

Purpurin (Verantin) is a reversible, competitive MAO-A inhibitor (Ki = 0.422 µM). This small molecule exhibits diverse bioactivities, including anti-angiogenic, antifungal, and antioxidative properties, making it a useful research tool for studying neurology, microbiology, and cancer biology in experimental models.

Research Area

Infectious Disease & Virology, Metabolism Research, Neuroscience

Key Properties

• CAS Number: 81-54-9
• MW: 256.21
• Purity: 98.00%
• Formula: C₁₄H₈O₅
• SMILES: Oc1cc(O)c2C(=O)c3ccccc3C(=O)c2c1O
• Target: Antibiotic,MAO,Antibacterial,Antifungal
• Solubility: DMSO:18.33 mg/mL (71.54 mM)

Bioactivity

• Target IC50:
  MAO-A:2.50μM(ki)
• In Vitro:
  Purpurin was a reversible and competitive inhibitor of MAO-A with a Ki value of 0.422μM. A comparison of their chemical structures suggested the 4-hydroxy group of purpurin might play an important role in its inhibition of MAO-A. Purpurin is a potent, selective, reversible inhibitor of MAO-A, and that it be considered a new potential lead compound for development of novel reversible inhibitors of MAO-A (RIMAs).

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Bacterial, Anthraquinone, antidepressant-like, Antibiotic, 1,2,4-Trihydroxyanthraquinone, inhibit, MAO-A, Inhibitor, Hydroxylizaric acid, Fungal, effects, Purpurin, Verantin

Compound Identifiers

PubChem CID

6683