Protopine

SKU: orb1304210

Description

Protopine (Fumarine) is a benzylisoquinoline alkaloid with research applications stemming from its activity as a histamine H1 receptor antagonist and inhibitor of platelet aggregation. It is utilized in pharmacological studies investigating analgesia, inflammation, and cardiovascular function in both in vitro and in vivo experimental models.

Research Area

Immunology & Inflammation, Metabolism Research, Neuroscience, Pharmacology & Drug Discovery, Signal Transduction

Key Properties

• CAS Number: 130-86-9
• MW: 353.37
• Purity: 99.54% (May vary between batches)
• Formula: C₂₀H₁₉NO₅
• SMILES: CN1CCc2cc3OCOc3cc2C(=O)Cc2ccc3OCOc3c2C1
• Target: Histamine Receptor,Platelet aggregation,Reactive Oxygen Species,Cholinesterase (ChE)
• Solubility: 10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (2.83 mM);DMSO:13.08 mg/mL (37.02 mM);Chloroform 1:15:Soluble

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Macleyine, inhibit, H1 receptor, Fumarine, Hypercorine, Inhibitor, Histamine Receptor, HistamineReceptor, Corydinine, Biflorine, Protopine, Platelet aggregation, platelet aggregation, Plateletaggregation, Reactive Oxygen Species, ReactiveOxygenSpecies

Compound Identifiers

PubChem CID

4970