PROTAC SOS1 degrader-9

SKU: orb2564535

Description

PROTACSOS1 degrader-8 (Compound 10) is a bifunctional degrader designed to selectively target SOS1 for ubiquitination and proteasomal degradation. This tool compound enables the investigation of SOS1-KRAS dependency in cancer research, with utility in both cellular and in vivo models for studying oncogenic signaling pathways.

Research Area

Pharmacology & Drug Discovery, Signal Transduction

Key Properties

• CAS Number: 3036155-21-9
• MW: 894.12
• Formula: C₅₁H₆₃N₁₁O₄
• SMILES: N([C@H](C)C1=C(C)C(C#N)=CC=C1)C=2C3=C(C=NC(=C3)N4CCN(C(=O)C5CCN(CC6CCC7(CC6)CCN(C(=O)C8=CC(=C(C)C=C8)N9C(=O)NC(=O)CC9)CC7)CC5)CC4)C(C)=NN2
• Target: PROTACs,Ras

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

171714347