PROTAC SMARCA2 degrader-9

SKU: orb2664965

Description

PROTAC SMARCA2 degrader-9 (compound I-285) is a PROTAC degrader targeting SMARCA2. It degrades SMARCA2 protein in A549 cells with a DC50 value of less than 100 nM and achieves a maximum degradation rate (Dmax%) of over 90% after 24 hours of treatment.

Key Properties

• CAS Number: 2568276-39-9
• MW: 758.87
• Formula: C₄₀H₄₆N₁₂O₄
• SMILES: O=C1NC(=O)C(N2C(=O)N(C3=CC(=CC=C32)CCCN4CCN(C5=CN=C(N=C5)N6C7CN(C=8C=C(N=NC8N)C9=CC=CC=C9O)CC6CC7)CC4)C)CC1
• Target: PROTACs

Storage & Handling

• Storage: -20°C
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

PROTACs