PROTAC FAK degrader 1

SKU: orb1707859

Description

PROTAC FAK degrader 1 is a potent and selective small molecule that induces the degradation of focal adhesion kinase (FAK) with an IC50 of 6.5 nM. This tool compound is valuable for investigating FAK's role in cancer cell migration, invasion, and proliferation in both in vitro and in vivo research models.

Research Area

Cardiovascular Research, Pharmacology & Drug Discovery, Signal Transduction

Key Properties

• CAS Number: 2301916-69-6
• MW: 996.13
• Formula: C₄₇H₅₆F₃N₉O₈S₂
• SMILES: CN(c1cccc(CNc2nc(Nc3ccc(OCCOCCC(=O)N[C@H](C(=O)N4C[C@H](O)C[C@H]4C(=O)NCc4ccc(cc4)-c4scnc4C)C(C)(C)C)cc3)ncc2C(F)(F)F)c1)S(C)(=O)=O
• Target: Akt,PROTACs,FAK

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

138454773