Defactinib analogue-1

SKU: orb2802428

Description

Defactinib analogue-1 (Compound 7) is a FAK-targeting ligand employed to construct PROTAC FAK degrader 1. This small molecule enables the study of FAK degradation and its role in cancer cell proliferation and migration in both cellular and animal models.

Research Area

Cardiovascular Research, Epigenetics & Chromatin, Immunology & Inflammation, Molecular Biology, Pharmacology & Drug Discovery, Signal Transduction

Images & Validation

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Key Properties

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CAS Number	2296719-34-9
MW	467.47
Formula	C₂₀H₂₀F₃N₅O₃S
SMILES	O=S(=O)(N(C1=CC=CC(=C1)CNC2=NC(=NC=C2C(F)(F)F)NC3=CC=C(O)C=C3)C)C
Target	PARP,PSMA,Ligands for Target Protein for PROTAC,FAK

Storage & Handling

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Storage	-20°C
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

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Compound Identifiers

PubChem CID

139291761 ↗

Key Properties

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No computed properties available.

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