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PROTAC CDK2/4 Degrader-1

SKU: orb3176613

Description

PROTACCDK2/4 Degrader-1 (Compound 5) is a potent CDK2/4 PROTAC degrader with a DC50 of ≤ 10 nM for both CDK2 and CDK4. It demonstrates excellent activity in inhibiting cell proliferation in OVCAR3 and T47D cell lines. This compound is applicable for breast cancer and ovarian cancer research.

Images & Validation

Key Properties

CAS Number3108138-84-4
MW674.77
FormulaC31H40F2N8O5S
SMILESO=C1NC(=O)C(C2=NN(C=3C=C(C=CC23)C4CCN(CCCS(=O)(=O)N5CCC(NC6=NC=C(OC(F)F)C=N6)CC5)CC4)C)CC1
TargetCDK,PROTACs

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Protocol Information