PROTAC CDK2/4/6 Degrader-2

SKU: orb3177263

Description

PROTACCDK2/4/6 Degrader-2 is a PROTAC degrader specifically targeting CDK2/4/6. It can react in a single step with pivaloyl chloride to convert into the prodrug PROTACCDK2/4/6 Degrader-1. In malignant melanoma cells, this compound effectively degrades CDK2/4/6 proteins and their complexes, leading to cell cycle arrest and apoptosis, with a pronounced effect on melanoma cells. PROTACCDK2/4/6 Degrader-2 is valuable for related malignant melanoma research.

Key Properties

• CAS Number: 2541626-49-5
• MW: 747.86
• Formula: C₄₀H₄₅N₉O₆
• SMILES: O=C(NCCCCCCNC1=CC=CC=2C(=O)N(C(=O)C12)C3C(=O)NC(=O)CC3)C4=CC=C(C=C4)NC=5N=CC=6C=C(C(=O)N(C)C)N(C6N5)C7CCCC7
• Target: CDK,PROTACs,Caspase

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

CDK,PROTACs,Caspase