PROTAC CDK2 Degrader-1

SKU: orb2665085

Description

PROTAC CDK2 Degrader-1 (Compound 41) is a heterobifunctional molecule that selectively degrades CDK2. It demonstrates functional activity by inhibiting RB phosphorylation in OVCAR3 cells with an IC50 of 100-500 nM. This tool compound is used in vitro to study CDK2's role in cell cycle progression and oncology research.

Research Area

Cell Biology, Epigenetics & Chromatin, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 3024971-78-3
• MW: 880.91
• Formula: C₃₈H₄₆F₆N₁₂O₄S
• SMILES: O=C1NC(=O)CCN1C2=NN(C=3C=C(C=CC23)C4CCN(CC4)CC5CCN(CC5)S(=O)(=O)N6CCC(NC=7N=CC(=C(N7)C=8C=NN(C8)CC(F)(F)F)C(F)(F)F)CC6)C
• Target: PROTACs,CDK

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

172652590