PROTAC CDK2/9 Degrader-1

SKU: orb1991290

Description

PROTAC CDK2/9 Degrader-1 is a bifunctional molecule that potently induces the degradation of both CDK2 and CDK9, with half-maximal degradation concentrations (DC50) of 62 nM and 33 nM, respectively. This compound serves as a valuable chemical probe for investigating cell cycle regulation and transcription in cancer research, applicable for both in vitro and in vivo experimental models.

Research Area

Cell Biology, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 2408641-24-5
• MW: 815.84
• Formula: C₄₀H₄₁N₁₃O₇
• SMILES: O=C(NC1=CC=C(C=C1)CN2CCN(C(=O)CCC(=O)NCCNC3=CC=CC=4C(=O)N(C(=O)C34)C5C(=O)NC(=O)CC5)CC2)C6=NNC=C6NC=7N=CN=C8NC=CC87
• Target: PROTACs,CDK

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

145925673