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PROTAC BCR-ABL1 ligand 1

SKU: orb1983340

Description

GMB-475 (PROTAC BCR-ABL1 ligand 1) is a small molecule that induces the degradation of the BCR-ABL1 oncoprotein by recruiting the VHL E3 ligase. This mechanism supports its investigation as a potential therapeutic strategy in chronic myeloid leukemia research, applicable in both cellular and animal models.

Research Area

Cardiovascular Research, Signal Transduction

Images & Validation

Key Properties

CAS Number2489876-34-6
MW347.29
FormulaC17H12F3N3O2
SMILESN(C1=CC(C2=CC=C(O)C=C2)=NC=N1)C3=CC=C(OC(F)(F)F)C=C3
TargetBcr-Abl,Others

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Key Properties

No computed properties available.

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Protocol Information

PROTAC BCR-ABL1 ligand 1 (orb1983340)

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