PRMT1 Antibody (C-term K342)

SKU: orb27862

Description

Rabbit polyclonal antibody to PRMT2 is a member of the protein arginine N-methyltransferase family. It is highly expressed in androgen target organs. It participates as a co-activator of the androgen receptor (AR)-mediated transactivation. Additionally, it inhibits NF-kappa-B transcription and promotes apoptosis.

Images & Validation

• Tested Applications: IHC-P, WB
• Dilution range: WB: 1:1000, IHC-P: 1:10-50
• Reactivity: Human, Mouse
• Predicted Reactivity: Rat

Key Properties

• Antibody Type: Primary Antibody
• Host: Rabbit
• Clonality: Polyclonal
• Isotype: Rabbit IgG
• Clone No.: RB15344
• Immunogen: Synthetic Peptide
• Target: PRMT1
• Molecular Weight: 42462
• Conjugation: Unconjugated

Storage & Handling

• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
• Form/Appearance: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
• Disclaimer: For research use only

Alternative Names

Anti-Protein Arginine N-Methyltransferase 1 antibody

Formalin-fixed and paraffin-embedded human breast carcinoma tissue reacted with PRMT1 antibody (C-term K342), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.

PRMT1 Antibody (C-term K342) western blot analysis in mouse Neuro-2a cell line lysates (35 ug/lane). This demonstrates the PRMT1 antibody detected the PRMT1 protein (arrow).

Western blot analysis of anti-PRMT1 Antibody (C-term K342) in Hela cell line lysates (35 ug/lane). PRMT1 (arrow) was detected using the purified Pab.

Quick Database Links

Gene Symbol

PRMT1

UniProt

Q99873

RefSeq (Protein):NP_001527.3, NP_938074.2