Prefusion glycoprotein F0/pre-F protein (RSV) Antibody

SKU: orb3158030

Description

Human respiratory syncytial virus (HRSV) is the most common etiological agent of acute lower respiratory tract disease in infants and can cause repeated infections throughout life. The RSV fusion glycoprotein (RSV F) is the principal target of RSV neutralizing antibodies in human sera. The RSV F is a type I viral fusion protein synthesized as inactive, single-chain polypeptides that assemble into trimers. RSV F fuses the viral and host cell membranes by irreversible protein refolding from the labile prefusion conformation to the stable post-fusion conformation. The antibody hRSV90 heavy chain interacts with residues 163–181 and site Ø, while the light chain interacts with residues 163–181 and site II.

Research Area

Infectious Disease & Virology; Musculoskeletal & Connective Tissue Research

Images & Validation

• Reactivity: Mouse

Key Properties

• Antibody Type: Recombinant Antibody
• Host: Human
• Clonality: Monoclonal
• Isotype: Human IgG1 | Human Kappa
• Target: Prefusion glycoprotein F0/pre-F protein (RSV)
• Source/Expression System: HEK293
• Purity: 0.9
• Conjugation: Unconjugated

Storage & Handling

• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Form/Appearance: Liquid
• Buffer/Preservatives: PBS, pH 7.4
• Expiration Date: 12 months from date of receipt.
• Dry Ice Shipping: Please note: This product requires shipment on dry ice. A dry ice surcharge will apply.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

Prefusion glycoprotein F0/pre-F protein (RSV)