Pramipexole

SKU: orb1308531

Description

Pramipexole (SND 919) is a selective dopamine D2/D3 receptor agonist primarily used in Parkinson's disease research. It is employed in both in vitro binding assays and in vivo models to study dopaminergic pathways, motor function, and potential neuroprotective effects.

Research Area

Neuroscience, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 104632-26-0
• MW: 211.33
• Purity: 99.96% (May vary between batches)
• Formula: C₁₀H₁₇N₃S
• SMILES: CCCN[C@H]1CCc2c(C1)sc(N)n2
• Target: Dopamine Receptor
• Solubility: H2O:< 1 mg/mL (insoluble or slightly soluble);DMSO:75 mg/mL (354.9 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (9.46 mM);Ethanol:39 mg/mL (184.55 mM)

Bioactivity

• Target IC50:
  D2S receptor:3.9 nM(Ki)|D2L receptor:2.2 nM(Ki)|D4 receptor:5.1 nM(Ki)|D3 receptor:0.5 nM(Ki)

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

D3, D2L, D4, Dopamine Receptor, Dopamine, disease, DopamineReceptor, cerebral, artery, Inhibitor, legs, occlusion, neurological, neuroprotection, Parkinson's, middle, inhibit, SND 919, SND919, SND-919, syndrome, RLS, restless, tMCAO, recovery, Pramipexole, transient

Compound Identifiers

PubChem CID

119570