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Catalog Number | orb1301055 |
---|---|
Category | Small Molecules |
Description | Pralatrexate |
CAS Number | 146464-95-1 |
Purity | 98.12% |
MW | 477.47 |
SMILES | NC=1C2=C(N=CC(CC(CC#C)C3=CC=C(C(N[C@@H](CCC(O)=O)C(O)=O)=O)C=C3)=N2)N=C(N)N1 |
Formula | C23H23N7O5 |
Biological Activity | Pralatrexate (10-Propargyl-10-deazaaminopterin) is a folate analogue inhibitor of dihydrofolate reductase (DHFR) exhibiting high affinity for reduced folate carrier-1 (RFC-1) with antineoplastic and immunosuppressive activities. |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
> 98% (HPLC) | |
146464-95-1 |
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