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PPARδ agonist 9
Catalog Number: orb2278393
| Catalog Number | orb2278393 |
|---|---|
| Category | Small Molecules |
| Description | PPARδ agonist 9 (compound 21), with an EC50 of 3.6 nM, effectively decreases serum MCP-1 concentrations in mice and significantly reduces atherosclerotic development in the LDLr-KO model with a 50-60% inhibition rate in vivo [1]. |
| Purity | 98.00% |
| MW | 569.04 |
| Biological Activity | PPARδ agonist 9 (compound 21), with an EC50 of 3.6 nM, is effective in vivo, decreasing serum MCP-1 concentrations in mice and markedly reducing atherosclerotic development in the LDLr-KO model with an inhibition rate of 50-60% [1]. |
| CAS Number | 928023-21-6 |
| Formula | C26H28ClF3N4O3S |
| SMILES | C(COC1=CC(CC(O)=O)=CC(Cl)=C1)C2(CCN(CC2)C=3SC=4C(N3)=CC=C(C(F)(F)F)N4)N5CCCC5 |
| Storage | -20°C |
| Note | For research use only |
L-165041 [orb1220484]
> 98% (HPLC)
79558-09-1
402.4
C22H26O7
50 mg, 5 mg, 2 mg, 10 mg, 25 mg, 100 mg, 1 g, 500 mg, 200 mg
