Poziotinib hydrochloride

• Catalog Number: orb1298656
• Category: Small Molecules
• Description: Poziotinib hydrochloride
• CAS Number: 1429757-68-5
• Purity: 99.69%
• MW: 527.8
• SMILES: Cl.COc1cc2ncnc(Nc3ccc(Cl)c(Cl)c3F)c2cc1OC1CCN(CC1)C(=O)C=C
• Formula: C₂₃H₂₂Cl₃FN₄O₃
• Biological Activity: Poziotinib hydrochloride irreversibly inhibits EGFR (HER1 or ErbB1), including EGFR mutants, HER2, and HER4, thereby inhibiting the proliferation of tumor cells that overexpress these receptors. It is an orally bioavailable, quinazoline-based pan epidermal growth factor receptor (EGFR or HER) inhibitor with potential antineoplastic activity.
• Note: For research use only
• Expiration Date: 12 months from date of receipt.