Polzastobart Biosimilar (LILRB2 / ILT4 / CD85d Reference Antibody）

SKU: orb2703966

Description

Polzastobart (JTX-8064) is a humanized IgG4 monoclonal antagonist antibody that selectively binds LILRB2 and prevents it from binding its ligands, classical and non-classical MHC I molecules. Polzastobart enhances pro-inflammatory cytokine production in macrophages by blocking the ability of LILRB2 to bind HLA-A/B and/or HLA-G, a marker of immunotolerance on cancer cells. Polzastobart is a macrophage immune checkpoint inhibitor.

Images & Validation

−

Key Properties

−

Antibody Type	Biosimilar Antibody
Clonality	Monoclonal
Target	Polzastobart Biosimilar（Anti-LILRB2 / ILT4 / CD85d Reference Antibody）
Purity	>98%
Conjugation	Unconjugated

Storage & Handling

−

Storage	Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Disclaimer	For research use only

Quality Guarantee

Explore bioreagents carefree to elevate your research. All our products are rigorously tested for performance. If a product does not perform as described on its datasheet, our scientific support team will provide expert troubleshooting, a prompt replacement, or a refund. For full details, please see our Terms & Conditions and Buying Guide. Contact us at [email protected].

Quick Database Links

Gene Symbol

Polzastobart Biosimilar（Anti-LILRB2 / ILT4 / CD85d Reference Antibody）

Documents Download

Datasheet

Product Information

Download

Request a Document

Protocol Information

Find More Protocols