PLD4 (N) Antibody, Rabbit Polyclonal

SKU: orb131748

Description

Rabbit polyclonal to PLD4. Phospholipase D4 (PLD4) is a single-pass membrane protein belonging to the phospholipase D family. PLD4 is mainly expressed in the ionized calcium binding adapter molecule 1 (Iba1)-positive microglia in the early postnatal mouse cerebellar white matter. Unlike its family members PLD1 and PLD2, PLD4 exhibits no enzymatic activity for conversion of phosphatidylcholine into choline and phosphatidic acid, and its function is completely unknown. A recent study suggests that the increased PLD4 in the activation process is involved in phagocytosis of activated microglia in the developmental stages and pathological conditions of white matter.

Research Area

Epigenetics, Immunology

Images & Validation

• Tested Applications: WB
• Dilution range: WB:1:1000-1:3000
• Reactivity: Human
• Application Notes:
  WB: The apparent protein size on WB may be different from the calculated M.W. due to modifications.; ; Experiment Notes: Rabbit polyclonal antibodies were produced by immunizing animals with a GST-fusion protein containing the N-terminal region of mouse PLD4.

Key Properties

• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: N-terminal region of mouse PLD4
• Molecular Weight: 56
• Purity: Affinity purification
• Conjugation: Unconjugated

Storage & Handling

• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Buffer/Preservatives: 0.01% NaN3
• Concentration: 100 μg/ml BSA
• Disclaimer: For research use only

Alternative Names

anti Phospholipase D4 antibody, anti PLD 4 antibody, anti Choline phosphatase 4 antibody, anti Phosphatidylcholine-hydrolyzing phospholipase D4 antibody, anti C14orf175 antibody

Quick Database Links

UniProt

Q96BZ4