Pladienolide B

SKU: orb3033155

Description

Pladienolide B is a potent cancer cell growth inhibitor that targets the SF3B1 subunit of the spliceosome. Pladienolide B exerts antitumor activities mediated through the inhibition of pre-mRNA splicing. Pladienolide B induces apoptosis.

Key Properties

• CAS Number: 445493-23-2
• MW: 536.697330474854
• Purity: >98%
• Formula: C₃₀H₄₈O₈
• SMILES: O1[C@H](C[C@@H](/C=C/C=C(\C)/[C@@H]2[C@@H](C)C=C[C@@H]([C@@](C)(CC[C@H](CC(=O)O2)O)O)OC(C)=O)C)[C@H]1[C@H](C)[C@H](CC)O |t:12|

Storage & Handling

• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only