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Piperlongumine

SKU: orb1225754

Description

A naturally occurring small molecule recently identified to be toxic selectively to cancer cells in vitro and in vivo; elevates cellular levels of reactive oxygen species (ROS) selectively in cancer cell lines, potently inhibits the growth of spontaneously formed malignant breast tumours and their associated metastases in mice; inhibits the STAT3 signal pathway in MM cells by binding directly to the STAT3 Cys712 residue.

Images & Validation

Key Properties

CAS Number20069-09-4
MW317.34
Purity>98% (HPLC)
FormulaC17H19NO5
SMILESO=C1C=CCCN1C(/C=C/C2=CC(OC)=C(OC)C(OC)=C2)=O
TargetSTAT
SolubilityDMSO: 31.7 mg/mL (100 mM) ( < 1 mg/ml refers to the product slightly soluble or insoluble )

Storage & Handling

StorageStorage temperature: -20°C. Stability: ≥ 2 years
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

Piplartine

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Piperlongumine (orb1225754)

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Available Sizes

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200 mg
500 mg
10 mg
$ 70.00
25 mg
$ 100.00
50 mg
$ 140.00
100 mg
$ 190.00